Importance of Organophosphorus Compounds in Medicinal Chemistry Field

Therapeutic importance of peptidomimetics in medicinal chemistry

Today there is a highly elevated demand for synthesis and screening of nature-like biopolymers and their more stable modified derivatives like peptidomimetics because availability of huge amounts of genomic and proteomic data can contribute for research in this area. The design and synthesis of peptidomimetics are most important because of the dominant position peptide and protein-protein inter...

Introduction of Medicinal Chemistry & Heterocyclic Compounds

Organophosphorus chemistry

Organophosphorus compounds are ubiquitous in nature, and due to their innate chemical properties, serve a fundamental role in a number of important fields. Among the more prominent features that elevate their status as a unique and versatile class of compounds, include variable oxidation states, multivalency, asymmetry and metal-binding properties. Their presence in bioactive natural products, ...

Medicinal and Biological Importance of 1,2,3-Triazoles in Click Chemistry

In this study, 1,2,3-Triazole derivatives have acquired conspicuous significance due to their wide spectrum of biological activities. There is a growing demand for the preparation of new antimicrobial agents due to the developing resistance towards conventional antibiotics, 1,2,3-Triazoles are an important class of organic compounds due to their wide applications in the synthesis of pharmaceuti...

Endophytes: A Treasure House of Bioactive Compounds of Medicinal Importance

Endophytes are an endosymbiotic group of microorganisms that colonize in plants and microbes that can be readily isolated from any microbial or plant growth medium. They act as reservoirs of novel bioactive secondary metabolites, such as alkaloids, phenolic acids, quinones, steroids, saponins, tannins, and terpenoids that serve as a potential candidate for antimicrobial, anti-insect, anticancer...